Conveniently located to serve the areas of Mesa, Tempe, Gilbert and Scottsdale, AZ

Daxxify is a new type of cosmetic treatment that can help reduce wrinkles and lines on the face, including frown lines and crow’s feet. It uses a technology called “peptide exchange” to help sustain its effect for up to six months, which is longer than some other similar treatments on the market. Some patients have even reported that it lasts up to nine months. When wrinkles and lines make your face look older or tired, it can affect your self-confidence and how you feel about your appearance. With Daxxify, you can enjoy smoother, younger-looking skin for longer without needing as many touch-ups or treatments.

Patients in Mesa, Tempe, Gilbert, and Scottsdale, AZ, can receive Daxxify injections from board-certified plastic surgeon Dr. Robert G. Bonillas. He is proud to offer Daxxify as a safe and effective option for his patients who want to improve the appearance of wrinkles and lines without surgery. If you are interested in Daxxify, scheduling a consultation to determine if this new injectable will help you meet your cosmetic goals is important. Contact Scottsdale Plastics today by calling (480) 245-6380 or completing our online form, and we will be in touch shortly. 

Join us on the Beauty Talk Blog for interesting articles and resources to offer insight into the treatments and procedures you want to know more about.

About Daxxify

Daxxify, the newest FDA-approved neuromodulator to hit the market, is an exciting alternative to Botox. Also called DaxibotulinumtoxinA, the injectable smooths existing lines and wrinkles and temporarily freezes the muscles that create new lines. 

The effects of current botulinum toxin products typically last only about three to four months after injection, requiring patients to repeat treatments regularly. To address this issue, Daxxify has been developed and formulated with a unique protein to enhance the delivery of botulinum toxin to nerve cells. 

Daxxify can treat: 

  • Glabellar lines – Vertical lines between the eyebrows due to repeated facial expressions and movements. They are often associated with aging and can make a person appear angry, tired, or stressed.
  • Cervical dystonia – A painful condition that causes involuntary contraction of the neck muscles. [1]

Glabellar lines are a type of dynamic wrinkle caused by repetitive facial movements, such as frowning, squinting, or concentrating. Over time, these dynamic wrinkles can become more prominent and develop into static wrinkles, which are visible even when the face is at rest.

What are Neuromodulators?

A neuromodulator is a chemical compound affecting how neurons or nerve cells communicate. They work by either enhancing or inhibiting the release of neurotransmitters, which are the chemical messengers that neurons use to communicate with the muscles. In cosmetic treatments like Daxxify, neuromodulators are typically used to reduce the appearance of wrinkles and lines on the face by temporarily relaxing the muscles that cause them.

When injected into the muscles of the face, neuromodulators can help to smooth out wrinkles and lines, giving the face a more youthful and rested appearance. The effects of a neuromodulator like Botox typically last for a few months before wearing off. Studies have shown that injectable DaxibotulinumtoxinA (Daxxify) can make the effects last longer because it diffuses less than other treatments. [2] In a study where the dose was increased gradually, 98% of the subjects who received the treatment noticed a reduction in the severity of glabellar lines after four weeks. [3]

What is Peptide Exchange Technology?

Daxxify’s peptide exchange technology binds to a peptide, which helps prevent the treatment breakdown and prolongs its effectiveness. The peptide is called RTP004, which comprises a chain of lysines, amino acids used by the body to build proteins. These lysines have a positive charge that helps the peptide bind tightly to the botulinum toxin. [4] Additionally, the peptide is free of any human or animal-derived components.

What are the Benefits of Daxxify?

One significant advantage of Daxxify is its extended duration, which translates to fewer visits to our office and reduced financial burden. Additionally, some other benefits of Daxxify are:

  • Reduction of dynamic wrinkles
  • Smoother “11 lines” or frown lines
  • Minimal side effects
  • Quick and easy treatment
  • No downtime
  • Customizable treatment

You can return to your normal activities immediately after your appointment, which makes this cosmetic improvement ideal for busy professionals. Daxxify is a safe and effective cosmetic treatment that can provide long-lasting results and help patients feel more confident in their appearance.

Who are the Ideal Candidates for Daxxify?

Neuromodulators are a popular and minimally-invasive option for people who want to improve their appearance without surgery or more invasive procedures. The ideal candidate for Daxxify is someone who is bothered by dynamic frown lines and wants a longer-lasting solution than some other similar treatments on the market. 

The patient should be in good general health and have realistic expectations for the treatment outcome. It is important to consult with a specialist like Dr. Bonillas to determine if Daxxify is the right option for your needs and goals. To schedule your consultation, call (480) 245-6380 today!

Personal Consultation

At Scottsdale Plastics, we understand that every patient has unique needs and goals regarding their appearance. That’s why we offer personalized consultations.

During your consultation, we will take the time to listen to your concerns and goals and will conduct a thorough evaluation to determine the best course of treatment for you. Whether you’re interested in Daxxify, or a surgical procedure like a facelift, we will work with you to find the best treatment course to treat your cosmetic concerns.

Dr. Bonillas is known for his compassionate and caring approach to patient care, and he takes great pride in helping his patients achieve their desired outcomes. He will take the time to explain all of your options in detail and will answer any questions you may have so that you can make an informed decision about your care.

To schedule your consultation, please contact our office today. We look forward to helping you achieve your cosmetic goals!


Preparing for Daxxify involves following certain instructions to ensure a safe and successful treatment. We will provide you with pre-treatment instructions before your Daxxify appointment.

Some common avoidances before treatment include Retin-A, blood thinners, Vitamin E supplements, and ibuprofen. However, this list is not exhaustive, and it is important to consult with us about any medications or supplements you are taking that may affect your treatment. Following these instructions can minimize the risk of bruising and complications and ensure the best possible results.

The Daxxify Injection Procedure

The Daxxify injection procedure involves using a small needle to inject the solution into the targeted areas. While the injection may cause a slight pinch, most patients report that the discomfort is mild and well-tolerated.

To ensure your comfort during the procedure, we will offer options for pain management. For example, we can ice the area or apply a numbing cream to minimize discomfort. We will also advise you on any steps you can take before or after the procedure to reduce the risk of discomfort or side effects.

Daxxify injections should be administered only once every three months. Our team will work with you to create a personalized treatment plan considering your needs and goals. We will advise you on the appropriate frequency of injections based on the areas being treated and the desired outcome. You can achieve the best possible results by following the recommended treatment schedule.

Recovery After Daxxify Injections

One of the benefits of Daxxify injections is that the procedure requires minimal downtime, so you can be on your way after your treatment is complete.

While it is normal to experience minor side effects, such as swelling, redness, or tenderness in the injection site, these usually resolve independently within a few hours or days. Mild bruising may occur due to the injection process, but it typically subsides within a few days.

What are the Results of Daxxify?

Results from treatment may be visible as soon as the day after the procedure and usually within 48 hours. Significant changes in the treated area can be seen within two weeks. Patients can enjoy smoother skin in the treatment area with fewer deep lines and a refreshed and rejuvenated appearance. Daxxify will slow the formation of new wrinkles and help maintain your skin’s youthful appearance over time.

Daxxify injections are not permanent and will typically last for 6-9 months. As the effects of the injections begin to wear off, you may notice the return of wrinkles and lines in the treated area.

To maintain the benefits of your injections, it is recommended that patients receive regular treatments at the appropriate intervals. Maintaining a healthy lifestyle and protecting your skin from sun damage and other environmental factors are also important. By taking good care of your skin and receiving regular Daxxify injections, you can enjoy a more youthful, refreshed appearance that lasts.

What is the Cost of Daxxify in Scottsdale, AZ?

To get an accurate idea of the cost of Daxxify injections at Scottsdale Plastics, schedule a consultation. We will be able to assess your individual needs and goals and provide you with an estimate of the cost of the procedure. Schedule your appointment today!


  1. Solish N, Carruthers J, Kaufman J, Rubio RG, Gross TM, Gallagher CJ. Overview of DaxibotulinumtoxinA for Injection: A Novel Formulation of Botulinum Toxin Type A. Drugs. 2021;81(18):2091-2101. https://doi.org/10.1007/s40265-021-01631-w
  2. Stone HF, Zhu Z, Thach TQD, Ruegg CL. Characterization of diffusion and duration of action of a new botulinum toxin type A formulation. Toxicon. 2011;58(2):159-167. https://doi.org/10.1016/j.toxicon.2011.05.012
  3. Garcia-Murray E, Velasco Villasenor ML, Acevedo B, et al. Safety and Efficacy of RT002, an Injectable Botulinum Toxin Type A, for Treating Glabellar Lines. Dermatologic Surgery. 2015;41(Supplement 1):S47-S55. https://doi.org/10.1097/dss.0000000000000276
  4. Carruthers J, Solish N, Humphrey S, et al. Injectable DaxibotulinumtoxinA for the Treatment of Glabellar Lines: A Phase 2, Randomized, Dose-Ranging, Double-Blind, Multicenter Comparison With OnabotulinumtoxinA and Placebo. Dermatologic Surgery. 2017;43(11):1321-1331. https://doi.org/10.1097/dss.0000000000001206